Improving mass spectrometry for better biomolecule quantification
Next Generation Elemental Mass Spectrometry of Nonmetals
['FUNDING_R01'] · GEORGETOWN UNIVERSITY · NIH-11045847
This study is exploring a new way to measure important molecules in the body quickly and accurately, which could help researchers better understand how different substances, like medications and toxins, affect our health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGETOWN UNIVERSITY (nih funded) |
| Locations | 1 site (WASHINGTON, UNITED STATES) |
| Trial ID | NIH-11045847 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing a new type of mass spectrometry technology that allows for the precise measurement of biomolecules without needing specific standards for each compound. By utilizing elemental properties of molecules, the method aims to quantify both small and large biomolecules rapidly and accurately. This is particularly important for understanding the biological effects of various substances, including drugs and environmental toxins. The innovative approach involves creating stable neutral species from elements and ionizing them for high-sensitivity detection, which could significantly advance analytical capabilities in biomedical research.
Who could benefit from this research
Good fit: Patients who are involved in studies related to drug metabolism, toxicity, or exposure to environmental contaminants may benefit from this research.
Not a fit: Patients not involved in drug treatment or exposure studies may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of biomolecules, improving the understanding of drug efficacy and toxicity.
How similar studies have performed: Other research has shown promise in enhancing mass spectrometry techniques, but this specific approach is relatively novel and untested.
Where this research is happening
WASHINGTON, UNITED STATES
- GEORGETOWN UNIVERSITY — WASHINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JORABCHI, KAVEH — GEORGETOWN UNIVERSITY
- Study coordinator: JORABCHI, KAVEH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.