NIH-funded research U01 cooperative agreement

Improving management of celiac disease with new gluten detection technologies

Official title: Evaluation of Novel Technologies to Improve Clinical Management of Celiac Disease: The GLUTECH Trial

Funded at Columbia University Health Sciences · NIH-10924061 · Data updated 2026-11-12

This study is exploring new ways to help adults with celiac disease manage their condition better by using handy gluten detection tools and telemedicine to make it easier for them to connect with dietitians and stay on track with their gluten-free diet.

More Celiac Disease research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 15, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$1,333,964
NIH project number5U01DK136523-02
Project IDNIH-10924061 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults diagnosed with celiac disease who are seeking better management strategies.

Less likely to help

Patients who do not have celiac disease or are not interested in using technology for self-monitoring may not benefit from this research.

What this research studies

This research investigates the effectiveness of innovative gluten detection technologies combined with telemedicine to enhance the management of celiac disease in adults. Celiac disease, affecting about 1% of the U.S. population, can lead to severe health issues if not properly managed. The study aims to facilitate better communication between patients and dietitians through telemedicine, while also empowering patients with tools for self-monitoring gluten exposure. By utilizing portable gluten sensors and urine tests, the research seeks to improve adherence to a gluten-free diet and overall quality of life for those affected.

Why it matters

Potential benefit: If successful, this research could significantly improve the management of celiac disease, leading to better health outcomes and quality of life for patients.

How similar studies have gone: Previous research has shown promising results with telemedicine and self-monitoring technologies in managing chronic conditions, indicating potential success for this approach.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Lebwohl, Benjamin — Columbia University Health Sciences
  • Study coordinator: Lebwohl, Benjamin

Related research

Other NIH-funded projects on the same topics.

  • Understanding how immune cells interact in celiac disease to guide healing

    A study from the University of Chicago will follow people with celiac disease to understand how immune cells in the gut contribute to damage or healing when gluten is present or restricted.

    NIH research University of Chicago · Chicago, United States · NIH-11465673

  • NanoDiscs: a new way to calm the immune system in celiac disease

    A new, protein-like particle called NanoDiscs is being developed to deliver safe targets to the immune system in people with celiac disease, with the goal of reducing reactions to gluten.

    NIH research Evoq Therapeutics, INC. · Ann Arbor, United States · NIH-11418898

  • Tissue damage and healing in Celiac Disease

    A broad study at the University of Chicago is exploring why some people with celiac disease keep having symptoms and tissue damage even when they try to follow a gluten-free diet.

    NIH research University of Chicago · Chicago, United States · NIH-11392285

  • Gluten-detection devices and telemedicine to help adults with celiac disease

    This project looks at whether using portable gluten sensors and urine gluten tests together with telemedicine can help adults with celiac disease stick to a gluten-free diet and feel better.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11370961

  • Gluten-sensing tech to help manage celiac disease with telemedicine

    A study tests new gluten-detection tools used with online care to help adults with celiac disease manage their condition.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11370183

  • Role of Transglutaminase 2 in Celiac Disease

    A study from Stanford aims to understand how a specific enzyme, TG2, contributes to celiac disease and to test a potential gut-focused treatment that could one day help people avoid dietary controls.

    NIH research Stanford University · Stanford, United States · NIH-11365566

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.