Improving malaria immunity in young children through preventive treatment
Enhancing immunity to malaria in young children with effective chemoprevention
['FUNDING_U01'] · STANFORD UNIVERSITY · NIH-10876295
This study is looking at ways to boost young children's immunity to malaria by giving special treatments to their mothers during pregnancy and to the kids in their early years, and it's for families in Uganda who want to help protect their little ones from malaria.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10876295 on ClinicalTrials.gov |
What this research studies
This research investigates how to enhance immunity to malaria in young children by using preventive treatments during pregnancy and early childhood. The study will focus on children born to mothers participating in a clinical trial in Uganda, where different treatment regimens will be tested. By preventing malaria infections during critical developmental periods, the research aims to improve the children's immune response to malaria. The approach involves monitoring the effects of these treatments on the children's health and immunity over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are young children, particularly those born to mothers who received preventive malaria treatment during pregnancy.
Not a fit: Patients who are older than 11 years or those who do not reside in malaria-endemic regions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce malaria-related morbidity and mortality in young children.
How similar studies have performed: Previous research has shown that preventive treatments can effectively reduce malaria incidence, suggesting potential success for this approach.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JAGANNATHAN, PRASANNA — STANFORD UNIVERSITY
- Study coordinator: JAGANNATHAN, PRASANNA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.