Improving lupus nephritis diagnosis using advanced imaging techniques

Improving the Accuracy of Lupus Nephritis Diagnosis using Biomarkers Derived from Ultraviolet and Mid-infrared Spectroscopic Imaging

['FUNDING_R01'] · UNIVERSITY OF HOUSTON · NIH-11005060

This study is looking to improve how doctors diagnose lupus nephritis by combining regular tissue examination with new imaging technology, making it easier to spot important details in kidney tissue that can help with accurate diagnosis.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF HOUSTON (nih funded)
Locations1 site (HOUSTON, UNITED STATES)
Trial IDNIH-11005060 on ClinicalTrials.gov

What this research studies

This research aims to enhance the diagnosis of lupus nephritis by integrating traditional histology with advanced imaging techniques. By using ultraviolet and mid-infrared spectroscopic imaging, the study seeks to provide a more accurate and comprehensive understanding of kidney tissue. This approach will help identify key structural and molecular features that are crucial for diagnosing lupus nephritis. The research will also employ deep learning to optimize the analysis of imaging data, potentially leading to better diagnostic outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with lupus nephritis, particularly those who may benefit from improved diagnostic accuracy.

Not a fit: Patients without lupus nephritis or those who do not require biopsy for diagnosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and reliable diagnoses of lupus nephritis, improving patient care and treatment outcomes.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for diagnosing various conditions, suggesting potential success for this novel approach.

Where this research is happening

HOUSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.