Improving lupus nephritis diagnosis using advanced imaging techniques
Official title: Improving the Accuracy of Lupus Nephritis Diagnosis using Biomarkers Derived from Ultraviolet and Mid-infrared Spectroscopic Imaging
Funded at University of Houston · NIH-11005060 · Data updated 2026-11-12
This study is looking to improve how doctors diagnose lupus nephritis by combining regular tissue examination with new imaging technology, making it easier to spot important details in kidney tissue that can help with accurate diagnosis.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | January 1, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $573,326 |
| NIH project number | 5R01DK135870-02 |
| Project ID | NIH-11005060 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with lupus nephritis, particularly those who may benefit from improved diagnostic accuracy.
✕Less likely to help
Patients without lupus nephritis or those who do not require biopsy for diagnosis may not benefit from this research.
What this research studies
This research aims to enhance the diagnosis of lupus nephritis by integrating traditional histology with advanced imaging techniques. By using ultraviolet and mid-infrared spectroscopic imaging, the study seeks to provide a more accurate and comprehensive understanding of kidney tissue. This approach will help identify key structural and molecular features that are crucial for diagnosing lupus nephritis. The research will also employ deep learning to optimize the analysis of imaging data, potentially leading to better diagnostic outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and reliable diagnoses of lupus nephritis, improving patient care and treatment outcomes.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for diagnosing various conditions, suggesting potential success for this novel approach.
Where this research is happening
-
University of Houston
Houston, United States Active
Researchers
- Principal investigator: Reddy, Rohith — University of Houston
- Study coordinator: Reddy, Rohith
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.