Improving lung transplant outcomes using imaging techniques
Improving lung transplant outcomes through the use of imaging in a DBD rat model
['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10198021
This study is looking at new ways to check the health of donor lungs, especially from brain-dead donors, to help improve the success of lung transplants and make sure patients get the best possible lungs for their surgery.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10198021 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing lung transplant outcomes by utilizing advanced imaging methods to assess the quality of donor lungs, particularly those from brain-dead donors. The study aims to understand how brain death affects lung viability and to develop strategies to mitigate complications associated with lung transplantation. By employing innovative imaging techniques, the research seeks to provide early and objective evaluations of lung health before transplantation, which could lead to better patient outcomes. The approach includes examining the structural, functional, and metabolic parameters of the lungs to identify suitable grafts for transplantation.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with end-stage lung disease who are awaiting lung transplantation.
Not a fit: Patients who are not candidates for lung transplantation or those with non-lung-related terminal conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and better overall outcomes for lung transplant recipients.
How similar studies have performed: Other research has shown promise in using imaging techniques to assess organ viability, suggesting that this approach could lead to significant advancements in lung transplantation.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RIZI, RAHIM R — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: RIZI, RAHIM R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.