Improving lung protection strategies for patients on mechanical ventilation
Implementation of behavioral economic approaches to improve evidence uptake for mechanically ventilated patients
This study is looking at ways to help doctors use safer breathing techniques for patients on ventilators, especially those with serious lung issues, by figuring out what stops them from using these methods and testing easy solutions to improve care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10614507 on NIH RePORTER |
What this research studies
This research investigates how to enhance the use of lung-protective ventilation (LPV) strategies for patients undergoing mechanical ventilation, particularly those with acute respiratory distress syndrome (ARDS). It aims to identify barriers that prevent clinicians from adopting LPV, such as lack of knowledge and diagnostic uncertainty. By utilizing electronic health records, the study will implement simple strategies to promote the uptake of LPV, potentially improving patient outcomes. The research will involve a large pragmatic trial to assess the effectiveness of these approaches in real-world clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who are undergoing mechanical ventilation, especially those diagnosed with ARDS or similar respiratory conditions.
Not a fit: Patients who are not on mechanical ventilation or do not have respiratory distress conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce mortality and long-term complications for patients requiring mechanical ventilation.
How similar studies have performed: Previous research has shown that lung-protective ventilation strategies can improve outcomes in similar patient populations, indicating a promising approach.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Kerlin, Meeta Prasad — University of Pennsylvania
- Study coordinator: Kerlin, Meeta Prasad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.