NIH-funded research U01 cooperative agreement

Improving lung health monitoring for workers exposed to hazardous environments

Official title: Enhancing Surveillance Spirometry of At-Risk Occupationally Exposed Populations

Funded at Icahn School of Medicine at Mount Sinai · NIH-10995057 · Data updated 2026-11-12

This study is looking to improve how we keep track of lung health for people who worked at the World Trade Center and were exposed to harmful substances, helping to spot any lung issues early on and find better ways to prevent them.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 1, 2024
Project endJune 30, 2026
Funding year2024
Award (this year)$349,999
NIH project number1U01OH012782-01
Project IDNIH-10995057 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who worked at the World Trade Center and are currently undergoing health surveillance for lung-related issues.

Less likely to help

Patients who have not been exposed to occupational hazards or do not have chronic lung conditions may not benefit from this research.

What this research studies

This research aims to enhance the monitoring of lung health in individuals who have been exposed to harmful substances in their workplace, particularly focusing on those who worked at the World Trade Center. The project will investigate various chronic lower airway diseases, identify risk factors, and assess lung function over time using advanced imaging techniques. By employing new surveillance tools and spirometry methods, the research seeks to improve early detection and prevention strategies for lung diseases in this at-risk population. Participants will be part of a cohort that has been closely monitored for their lung health since their exposure.

Why it matters

Potential benefit: If successful, this research could lead to better monitoring and management of lung diseases in occupationally exposed individuals, potentially improving their quality of life.

How similar studies have gone: Previous research has shown promising results in monitoring lung health in similar occupational cohorts, indicating that this approach may be effective.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: De la Hoz, Rafael E. — Icahn School of Medicine at Mount Sinai
  • Study coordinator: De la Hoz, Rafael E.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.