Improving Lung Health for People with HIV and COPD
Resetting the Clock in HIV associated COPD
['FUNDING_R01'] · FLORIDA INTERNATIONAL UNIVERSITY · NIH-11116910
This research looks at how the body's natural daily rhythms might be connected to lung problems like COPD in people living with HIV.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA INTERNATIONAL UNIVERSITY (nih funded) |
| Locations | 1 site (MIAMI, UNITED STATES) |
| Trial ID | NIH-11116910 on ClinicalTrials.gov |
What this research studies
Many people living with HIV experience increased lung inflammation and a higher chance of developing COPD, even when accounting for smoking. Our bodies have an internal 'molecular clock' that helps regulate various functions, including how our lungs respond to inflammation. This clock can be disrupted by both HIV and smoking, potentially leading to more severe lung issues. This project aims to uncover how these disruptions in the lung's molecular clock contribute to COPD in individuals with HIV. By understanding this connection, we hope to find new ways to protect lung health.
Who could benefit from this research
Good fit: This research is relevant for individuals living with HIV, especially those who experience lung inflammation or have been diagnosed with COPD.
Not a fit: Patients seeking immediate new treatments or direct clinical intervention will not directly benefit from this foundational research.
Why it matters
Potential benefit: Successfully understanding this connection could lead to new treatments or prevention strategies for lung disease in people living with HIV.
How similar studies have performed: While disruptions of the lung molecular clock have been implicated in COPD and smoking, this specific link to HIV-associated COPD is a novel area of focus.
Where this research is happening
MIAMI, UNITED STATES
- FLORIDA INTERNATIONAL UNIVERSITY — MIAMI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: UNWALLA, HOSHANG JEHANGIR — FLORIDA INTERNATIONAL UNIVERSITY
- Study coordinator: UNWALLA, HOSHANG JEHANGIR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus