Improving Lung Function Monitoring for World Trade Center Responders

Enhancing Surveillance Spirometry of At-Risk Occupationally Exposed Populations

['FUNDING_U01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11174197

This project aims to find better ways to monitor lung health and prevent chronic lung diseases in World Trade Center workers and volunteers.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11174197 on ClinicalTrials.gov

What this research studies

We are working to understand the different types of chronic lung diseases seen in World Trade Center (WTC) workers and volunteers, looking at what causes them and other health issues they might have. Our goal is to identify groups of people whose lung function changes over time in different ways and to use new imaging techniques to understand lung injuries. We are also exploring new tools for checking lung health and different ways to track how lung function changes over many years. This work includes testing new methods for calibrating spirometry equipment, which could make it easier to perform lung tests in more places.

Who could benefit from this research

Good fit: This project focuses on World Trade Center workers and volunteers who are part of the existing occupational cohort followed at Mount Sinai.

Not a fit: Patients not exposed to the World Trade Center events or not part of the Mount Sinai cohort would not directly benefit from this specific project.

Why it matters

Potential benefit: If successful, this work could lead to earlier detection of lung problems and more effective strategies to prevent chronic lung disease in at-risk individuals.

How similar studies have performed: Previous research has suggested different patterns of lung function changes and early markers of chronic lung disease in WTC workers, building on existing knowledge.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.