Improving lung function imaging to lessen side effects in lung cancer treatment
Quantitative Lung Function Imaging to Reduce Toxicity for patients treated with Radiation and Immunotherapy
This study is looking at how to help lung cancer patients who are getting radiation and immunotherapy by using a new imaging technique to create detailed maps of their lung function, so doctors can tailor treatment plans that protect healthy lung areas and reduce the risk of serious side effects like pneumonitis, ultimately aiming to improve patients' quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10925415 on NIH RePORTER |
What this research studies
This research focuses on lung cancer patients undergoing radiotherapy and immunotherapy, who are at risk of developing serious lung side effects, particularly pneumonitis. The project aims to utilize a novel lung function imaging technique that creates detailed maps of lung function using data from routine clinical care. By implementing a personalized radiation treatment plan that avoids damaging functional areas of the lung, the research seeks to reduce the incidence of pneumonitis and improve patients' quality of life. The approach combines advanced imaging with innovative software techniques to enhance treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are lung cancer patients who are being treated with both radiotherapy and immunotherapy.
Not a fit: Patients who are not undergoing radiotherapy or immunotherapy for lung cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of pneumonitis and improve the quality of life for lung cancer patients receiving aggressive treatments.
How similar studies have performed: Previous research has shown promise in using imaging techniques to guide treatment plans, suggesting that this approach could lead to meaningful advancements in patient care.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Vinogradskiy, Yevgeniy — Thomas Jefferson University
- Study coordinator: Vinogradskiy, Yevgeniy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.