Improving lung cancer treatment with advanced imaging and radiation techniques
Official title: High-Precision Lung Radiotherapy by Intra-treatment Dynamic Cone-beam CT imaging and Dosimetry-guided Plan Adaptation
Funded at Ut Southwestern Medical Center · NIH-11096051 · Data updated 2026-11-12
This study is looking at new ways to make lung cancer radiation treatment more accurate by using special imaging techniques during the procedure, so patients can get better tumor targeting and fewer side effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | June 1, 2024 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $499,826 |
| NIH project number | 5R01EB034691-02 |
| Project ID | NIH-11096051 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with lung cancer, particularly those with centrally located tumors requiring radiation therapy.
✕Less likely to help
Patients with non-lung cancers or those who are not candidates for radiation therapy may not benefit from this research.
What this research studies
This research focuses on enhancing the precision of lung cancer radiotherapy by utilizing advanced imaging techniques during treatment. It aims to address the challenges posed by the movement of lung tumors and surrounding organs, which can lead to inaccurate radiation delivery. By employing intra-treatment dynamic imaging and adapting radiation plans based on real-time data, the study seeks to optimize the effectiveness of stereotactic body radiation therapy (SBRT) while minimizing damage to healthy tissues. Patients undergoing this treatment may benefit from improved targeting of tumors and reduced side effects.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer lung cancer treatments with fewer side effects.
How similar studies have gone: Previous studies have shown promise in using advanced imaging techniques to improve radiation therapy outcomes, indicating that this approach has potential for success.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Zhang, You — Ut Southwestern Medical Center
- Study coordinator: Zhang, You
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.