Improving lung cancer treatment for veterans using immunotherapy
Repositioning Immunotherapy in Veterans with Lung Cancer
This study is looking at a new treatment plan that combines immunotherapy and chemotherapy before surgery for veterans with advanced lung cancer, hoping to make the treatment easier to handle and help them live longer without the cancer getting worse.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10916686 on NIH RePORTER |
What this research studies
This research investigates the use of neoadjuvant immunotherapy combined with chemotherapy for veterans diagnosed with unresectable Stage III lung cancer. The approach aims to enhance treatment tolerance and improve progression-free survival rates by administering immunotherapy before surgery. The study will also explore the use of PET-adaptive radiotherapy to optimize treatment delivery and minimize side effects. By focusing on veterans, the research addresses a critical need for more effective and manageable treatment options in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with unresectable Stage III non-small cell lung cancer who are seeking alternative treatment options.
Not a fit: Patients with resectable lung cancer or those who are not veterans may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and better quality of life for veterans with lung cancer.
How similar studies have performed: Previous research has shown promising results with neoadjuvant immunotherapy in other cancers, suggesting potential success in this approach for lung cancer.
Where this research is happening
Ann Arbor, United States
- Veterans Health Administration — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Ramnath, Nithya — Veterans Health Administration
- Study coordinator: Ramnath, Nithya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.