Improving lung cancer treatment by managing breathing motion during radiotherapy

Personalized Motion Management for Truly 4D Lung Radiotherapy

NIH-funded research University of Maryland Baltimore · NIH-10877734

This study is looking to make lung cancer radiation treatment better by tracking how your lungs move while you breathe, using advanced imaging technology, so that the radiation can hit the right spots more accurately, which could lead to safer and more effective treatment for you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10877734 on NIH RePORTER

What this research studies

This research focuses on enhancing lung cancer radiotherapy by addressing the challenges posed by patients' breathing motion. It aims to develop a new real-time motion management solution that combines advanced imaging techniques, specifically 4D MRI and 4D CT, to create a detailed model of how a patient's lungs move during treatment. By capturing this complex motion, the goal is to ensure that radiation is delivered more accurately, reducing the risk of treatment failure and side effects. Patients may benefit from more effective and safer radiotherapy as a result of this innovative approach.

Who could benefit from this research

Good fit: Ideal candidates for this research are lung cancer patients undergoing radiotherapy who experience significant breathing motion.

Not a fit: Patients with non-thoracic cancers or those not receiving radiotherapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more precise and effective lung cancer treatments, minimizing side effects and improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for motion management in radiotherapy, indicating potential for success in this novel approach.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.