Improving lung cancer screening benefits and risks for older adults

Applying causal inference methods to improve estimation of the real-world benefits and harms of lung cancer screening - NCI Diversity Supplement

['FUNDING_R01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11062596

This study is looking at how well lung cancer screening with low-dose CT scans works in real life for older adults, focusing on the real benefits and risks, so we can make these screening programs better for everyone.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIV OF NORTH CAROLINA CHAPEL HILL (nih funded)
Locations1 site (CHAPEL HILL, UNITED STATES)
Trial IDNIH-11062596 on ClinicalTrials.gov

What this research studies

This research investigates how lung cancer screening using low-dose computed tomography can be better understood in real-world settings, especially for older adults. It aims to identify the actual benefits and harms of screening, considering factors that may differ from clinical trials. By analyzing data on screening uptake and adherence, the study seeks to provide insights that could enhance the effectiveness of lung cancer screening programs in everyday clinical practice.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 65 and older who are eligible for lung cancer screening.

Not a fit: Patients who are younger than 65 or those who do not meet the eligibility criteria for lung cancer screening may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved lung cancer screening strategies that better serve older adults, potentially reducing mortality rates.

How similar studies have performed: Previous research has shown that real-world evidence can significantly inform and improve clinical practices, suggesting that this approach may yield valuable insights.

Where this research is happening

CHAPEL HILL, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.