Improving lung cancer screening benefits and risks for older adults
Official title: Applying causal inference methods to improve estimation of the real-world benefits and harms of lung cancer screening - NCI Diversity Supplement
Funded at Univ of North Carolina Chapel Hill · NIH-11062596 · Data updated 2026-11-12
This study is looking at how well lung cancer screening with low-dose CT scans works in real life for older adults, focusing on the real benefits and risks, so we can make these screening programs better for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $75,159 |
| NIH project number | 3R01CA277756-02S1 |
| Project ID | NIH-11062596 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who are eligible for lung cancer screening.
✕Less likely to help
Patients who are younger than 65 or those who do not meet the eligibility criteria for lung cancer screening may not benefit from this research.
What this research studies
This research investigates how lung cancer screening using low-dose computed tomography can be better understood in real-world settings, especially for older adults. It aims to identify the actual benefits and harms of screening, considering factors that may differ from clinical trials. By analyzing data on screening uptake and adherence, the study seeks to provide insights that could enhance the effectiveness of lung cancer screening programs in everyday clinical practice.
Why it matters
Potential benefit: If successful, this research could lead to improved lung cancer screening strategies that better serve older adults, potentially reducing mortality rates.
How similar studies have gone: Previous research has shown that real-world evidence can significantly inform and improve clinical practices, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Lund, Jennifer — Univ of North Carolina Chapel Hill
- Study coordinator: Lund, Jennifer
Related research
Other NIH-funded projects on the same topics.
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Digital health strategies to expand lung cancer screening in safety-net clinics
A funded project aims to help low-resource clinics increase the use of lung cancer screening for patients who smoke or are at risk.
-
Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
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Population health approach to boost lung cancer screening at community clinics
A large Utah project aims to help community clinics reach more eligible adults to get low-dose CT lung cancer screening.
-
Group-based tobacco treatment for older adults after lung cancer screening
A study tests a group-based tobacco cessation program for older adults who are getting lung cancer screening to help them quit smoking.
-
Personalized Lung Cancer Screening for Veterans
Aimed at improving who gets screened and how lung cancer is diagnosed among Veterans using personalized tools.
-
Proteogenomic framework to improve lung cancer screening with biomarkers
A biomarker-based approach aims to refine LDCT lung cancer screening so more cancers are caught early while reducing unnecessary procedures.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.