Improving lung cancer screening and smoking cessation for at-risk patients
Official title: Precision prevention strategy to increase uptake and engagement in lung cancer screening and smoking cessation treatment
Funded at Washington University · NIH-11057507 · Data updated 2026-11-12
This study is looking to help current and former smokers, especially those in underserved communities like African Americans, get better access to lung cancer screenings and support to quit smoking by using a special tool that helps doctors and patients talk about their lung cancer risks and treatment options in a more personal way.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | March 21, 2022 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $579,054 |
| NIH project number | 5R01CA268030-04 |
| Project ID | NIH-11057507 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include current and former smokers, particularly those from African American communities, who are at risk for lung cancer.
✕Less likely to help
Patients who do not smoke or have never smoked, as well as those who are not at risk for lung cancer, may not benefit from this research.
What this research studies
This research aims to enhance the uptake of lung cancer screening and smoking cessation treatments among current and former smokers, particularly focusing on underserved populations like African Americans. It employs a multi-level intervention that includes a precision risk tool designed to encourage both physicians and patients to engage in discussions about lung cancer risks and treatment options. By integrating clinical and genetic factors, the study seeks to motivate behavior change and improve patient outcomes through personalized feedback. The approach emphasizes the importance of patient-centered care and aims to bridge existing gaps in healthcare delivery.
Why it matters
Potential benefit: If successful, this research could significantly increase the number of patients receiving timely lung cancer screenings and effective smoking cessation treatments, ultimately reducing lung cancer mortality.
How similar studies have gone: Previous research has shown that personalized interventions can effectively increase engagement in cancer screening and smoking cessation, indicating a promising approach in this area.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Ramsey, Alex Taylor — Washington University
- Study coordinator: Ramsey, Alex Taylor
Related research
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Personalized lung cancer risk tool to boost screening and help people quit smoking
This project uses a personalized risk profile to help current and former smokers—particularly underserved and African American patients—get lung cancer screening and stop smoking.
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Improving lung cancer screening and smoking cessation for African Americans
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I-STOP: a mobile health program to help people with HIV quit smoking
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.