NIH-funded research R01 grant

Improving long-term weight loss maintenance strategies

Official title: Optimizing an extended care intervention to promote weight loss maintenance

Funded at University of Alabama at Birmingham · NIH-11078222 · Data updated 2026-11-12

This study is looking for ways to help people keep off the weight they've lost by trying out easy strategies, like eating fewer different foods and doing simple exercises at home, and it's open to anyone who has lost at least 5% of their body weight.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham
NIH-funded
Lab location1 site (Birmingham, United States)
Project startMay 1, 2024
Project endFebruary 28, 2029
Funding year2025
Award (this year)$633,603
NIH project number5R01DK139059-02
Project IDNIH-11078222 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults aged 21 and older who have recently achieved significant weight loss and are looking for support in maintaining that weight loss.

Less likely to help

Patients who are not currently engaged in a weight loss program or those who have not lost weight may not benefit from this research.

What this research studies

This research investigates ways to help individuals maintain weight loss after an initial weight loss phase. It focuses on developing and testing various low-effort strategies that can support ongoing weight management, such as reducing food variety and incorporating home-based exercise. Participants who have lost at least 5% of their body weight will be involved in a 12-month trial where they may receive different combinations of these supportive interventions. The goal is to find effective methods that require minimal effort from participants while still promoting adherence to weight loss maintenance behaviors.

Why it matters

Potential benefit: If successful, this research could provide patients with easier and more sustainable methods for maintaining weight loss over the long term.

How similar studies have gone: Previous research has shown that behavioral interventions can be effective for weight loss, but this approach is novel in its focus on minimizing participant burden.

Where this research is happening

  • University of Alabama at Birmingham
    Birmingham, United States
    Active

Researchers

  • Principal investigator: Dutton, Gareth R — University of Alabama at Birmingham
  • Study coordinator: Dutton, Gareth R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.