NIH-funded research U01 cooperative agreement

Improving liver cancer care for HIV patients in Uganda

Official title: Leveraging HIV care infrastructure for implementation of context-adapted liver cancer comprehensive control strategies in Uganda: The LC3 Study

Funded at Johns Hopkins University · NIH-11001696 · Data updated 2026-11-12

This study is looking to improve how we prevent and treat liver cancer for people living with HIV in Uganda by combining liver cancer care with their current HIV services, making it easier for patients to get the help they need.

More Liver Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startSeptember 3, 2024
Project endAugust 31, 2029
Funding year2024
Award (this year)$632,241
NIH project number1U01CA275117-01A1
Project IDNIH-11001696 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults living with HIV in Uganda, particularly those at risk for hepatitis B co-infection.

Less likely to help

Patients who are not living with HIV or hepatitis B may not benefit from this research.

What this research studies

This research aims to enhance liver cancer control strategies by integrating them into existing HIV care services in Uganda. It focuses on understanding the co-infection of hepatitis B and HIV, and the resulting risks of liver cancer. The project will implement a comprehensive package of prevention, screening, and treatment interventions tailored to the local context, addressing barriers to care. By leveraging over 18 years of collaborative research, the study seeks to improve clinical management and outcomes for patients at risk of liver cancer.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence and mortality of liver cancer among HIV patients in Uganda.

How similar studies have gone: Previous research has shown success in integrating hepatitis B services into HIV care, indicating a promising approach for this study.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Kirk, Gregory D — Johns Hopkins University
  • Study coordinator: Kirk, Gregory D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.