Improving leukemia treatment and research at Washington University
Official title: Clinician Scientist in Leukemia
Funded at Washington University · NIH-10930806 · Data updated 2026-11-12
This study is all about finding better ways to treat leukemia, especially for older adults and those from underrepresented backgrounds, by running new clinical trials and looking at how social factors affect health, so we can help more people achieve better outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $132,781 |
| NIH project number | 5R50CA275927-02 |
| Project ID | NIH-10930806 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients diagnosed with leukemia, particularly older adults with acute myeloid leukemia.
✕Less likely to help
Patients with leukemia who are not eligible for clinical trials or those with advanced disease that does not respond to current treatments may not benefit from this research.
What this research studies
This research focuses on enhancing the clinical management of leukemia through improved operational efficiency and expanded capabilities at Washington University School of Medicine. The project aims to implement high-quality clinical trials that can lead to better treatment outcomes for patients with leukemia. It also emphasizes addressing health disparities by increasing participation from underrepresented minorities and evaluating the impact of social factors on health. Additionally, the research will explore innovative treatment combinations for older adults with acute myeloid leukemia (AML) to improve remission rates.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and improved outcomes for patients with leukemia.
How similar studies have gone: Previous research has shown success in improving leukemia treatment through innovative clinical trials and targeted therapies, indicating a promising approach.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Uy, Geoffrey L — Washington University
- Study coordinator: Uy, Geoffrey L
Related research
Other NIH-funded projects on the same topics.
-
Investigating a specific type of leukemia in children caused by genetic changes.
This study is looking at how certain proteins linked to leukemia affect kids and teens with high-risk blood cancers, and the researchers hope to find new ways to treat these conditions by learning more about how the disease works.
-
Caregiver-led mobile tool to support healthy habits for kids treated for ALL
A caregiver-directed mobile program helps children who were treated for acute lymphoblastic leukemia build healthier daily routines.
-
Targeting the SCP4 pathway in acute myeloid leukemia (AML)
Aims to uncover how the SCP4 signaling pathway drives AML and how it could be blocked to help patients.
-
Understanding TCRs in Leukemia to Improve Immunotherapies
A short, patient-friendly look at a project trying to map how immune cells recognize leukemia so future therapies can be better and safer for people with AML.
-
Targeted therapy for AML using DHODH inhibitors to boost differentiation and immune response
Aims to help adults with acute myeloid leukemia by using a special drug approach that makes cancer cells act more like normal blood cells and supports the immune system.
-
Genomics of childhood ALL across global populations
A wide-ranging study looks at how inherited genetics influence the risk of childhood acute lymphoblastic leukemia around the world.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.