NIH-funded research R01 grant

Improving learning and memory in people with Multiple Sclerosis

Official title: Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS

Funded at Kessler Foundation, INC. · NIH-10860921 · Data updated 2026-11-12

This study is testing a special program to help people with Multiple Sclerosis improve their learning and memory skills through fun strategies, and it’s designed to see if these techniques can really make a difference in their daily lives.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKessler Foundation, INC.
NIH-funded
Lab location1 site (East Hanover, UNITED STATES)
Project startMay 10, 2019
Project endSeptember 30, 2025
Funding year2024
Award (this year)$344,010
NIH project number5R01HD095915-05
Project IDNIH-10860921 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Multiple Sclerosis who experience difficulties with new learning and memory.

Less likely to help

Patients without cognitive impairments or those not diagnosed with Multiple Sclerosis may not benefit from this research.

What this research studies

This research investigates a structured program designed to enhance learning and memory in individuals with Multiple Sclerosis (MS). It involves an 8-session cognitive rehabilitation protocol that teaches participants effective strategies such as self-generation, spaced learning, and self-testing. The study will be conducted as a double-blind, placebo-controlled trial, meaning neither the participants nor the researchers will know who is receiving the actual treatment versus a placebo. The goal is to determine if these strategies can significantly improve cognitive function and quality of life for those affected by MS.

Why it matters

Potential benefit: If successful, this research could lead to effective cognitive rehabilitation techniques that improve memory and learning for patients with Multiple Sclerosis.

How similar studies have gone: Previous research has shown promise in cognitive rehabilitation approaches for improving memory in various populations, suggesting potential success for this novel application in MS.

Where this research is happening

  • Kessler Foundation, INC.
    East Hanover, United States
    Active

Researchers

  • Principal investigator: Chiaravalloti, Nancy D. — Kessler Foundation, INC.
  • Study coordinator: Chiaravalloti, Nancy D.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.