Improving large-scale detection of emerging pathogens using advanced sequencing technology
Expanding Swabseq sequencing technology to enable readiness for emerging pathogens
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10886137
This study is working on a new way to quickly and accurately find germs like COVID-19 by testing many samples at the same time, making it easier for more labs to help keep everyone safe.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10886137 on ClinicalTrials.gov |
What this research studies
This research focuses on developing enhanced methods for detecting novel pathogens, such as COVID-19, through a large-scale testing approach. By utilizing next-generation sequencing technology, the study aims to analyze hundreds of thousands of samples simultaneously. Each sample is labeled with a unique DNA barcode, allowing for efficient pooling and testing of multiple samples at once. This method not only increases testing capacity but also aims to make high-throughput testing accessible to more laboratories.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who may be asymptomatic carriers of emerging pathogens or those in high-risk environments requiring frequent testing.
Not a fit: Patients who are not at risk for emerging pathogens or those who do not require frequent testing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the speed and efficiency of pathogen detection, leading to better public health responses during outbreaks.
How similar studies have performed: Previous research has shown success with similar high-throughput sequencing approaches in pathogen detection, particularly during the COVID-19 pandemic.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ESKIN, ELEAZAR — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: ESKIN, ELEAZAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.