Improving language skills in infants at risk for autism

PETAL: Promoting Early Intervention Timing and Attention to Language

NIH-funded research University of California Los Angeles · NIH-11089530

This study is looking at the best time to start a special program for babies who might be at higher risk for autism because they have an older sibling with the condition, to help them develop their communication and language skills by the time they turn 2 years old.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11089530 on NIH RePORTER

What this research studies

This research investigates the timing of a parent-mediated intervention aimed at infants who are at increased risk for autism due to having an older sibling with the condition. The study will assess when to start interventions—at 9, 12, or 15 months—to best support communication and language development by 24 months. By utilizing a combination of brain and behavioral markers, the research aims to identify effective strategies for enhancing language skills in these infants. The study will involve 140 infants and will take place in the Los Angeles and Boston areas.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants aged 6 months to 15 months who have an older sibling diagnosed with autism.

Not a fit: Patients who do not have a family history of autism or are outside the specified age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved language outcomes for infants at risk for autism, potentially reducing the impact of language delays.

How similar studies have performed: Previous research has shown promise in early interventions for language development in at-risk populations, but this specific timing approach is relatively novel.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions autism spectral disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.