Improving knee imaging using advanced techniques
Official title: Advanced Knee ASL Imaging at 7T
Funded at University of Minnesota · NIH-10843321 · Data updated 2026-11-12
This study is testing a new way to take detailed pictures of the bone marrow in your knee using a special type of MRI, which could help doctors better understand and treat conditions like arthritis.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $370,853 |
| NIH project number | 5R01EB033365-02 |
| Project ID | NIH-10843321 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults and adolescents with knee issues, particularly those suffering from degenerative arthritis.
✕Less likely to help
Patients with conditions unrelated to knee health or those who are not within the age range of 21 years and older may not benefit from this research.
What this research studies
This research focuses on enhancing the imaging of knee bone marrow using advanced arterial spin labeling (ASL) magnetic resonance imaging (MRI) at a high magnetic field strength of 7T. By utilizing this noninvasive technique, the study aims to better understand bone physiology and disease progression, particularly in conditions like degenerative arthritis. The approach addresses existing challenges in imaging quality and reliability, allowing for more accurate monitoring of treatment responses over time. Patients may benefit from improved diagnostic capabilities and personalized treatment plans based on their bone health.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment monitoring for patients with knee-related conditions.
How similar studies have gone: Previous research has shown promise in using advanced MRI techniques for improved imaging, suggesting potential success for this novel approach.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Li, Xiufeng — University of Minnesota
- Study coordinator: Li, Xiufeng
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.