Improving kidney transplants between HIV-positive patients in South Africa
Maximizing the success of HIV+ to HIV+ kidney transplantation in South Africa
This study is looking at how well kidney transplants work for people living with HIV, especially focusing on their health and the chances of their new kidney being accepted, to help improve transplant services for those in need in South Africa.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cape Town NIH-funded |
| Lab location | 1 site (Rondebosch, South Africa) |
| Project ID | NIH-10840812 on NIH RePORTER |
What this research studies
This research investigates the outcomes of kidney transplants between HIV-positive patients, focusing on patient and graft survival rates. It aims to understand how immune modulators affect the HIV latent viral reservoir, which is crucial for finding a cure for HIV. The study also examines the risk of organ rejection in these patients and seeks to enhance transplantation services in underserved areas of South Africa. By collaborating with experts in HIV and transplantation, the research aims to improve clinical practices and patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-positive individuals in need of a kidney transplant.
Not a fit: Patients who are not HIV-positive or those who do not require a kidney transplant may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective kidney transplants for HIV-positive patients, improving their quality of life.
How similar studies have performed: Previous research has shown comparable survival rates for HIV-positive kidney transplant recipients, indicating a promising approach in this area.
Where this research is happening
Rondebosch, South Africa
- University of Cape Town — Rondebosch, South Africa (Active)
Researchers
- Principal investigator: Muller, Elmi — University of Cape Town
- Study coordinator: Muller, Elmi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.