Improving kidney transplantation through advanced organ preservation techniques
Organ banking for transplant--kidney cryopreservation by vitrification and novel nanowarming technology
This study is exploring new ways to keep kidneys healthy for longer so they can be better matched with patients who need transplants, helping to solve the shortage of available organs and improve transplant success.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11054624 on NIH RePORTER |
What this research studies
This research focuses on developing innovative methods to preserve kidneys for transplantation using cryopreservation and nanowarming technology. By cooling kidneys rapidly to prevent ice formation, the study aims to extend the viability of donor organs, allowing for better matching with recipients and improved outcomes. The approach seeks to address the significant shortage of available organs by enabling the banking of kidneys, which could enhance patient preparation and increase overall organ utilization. The research involves both laboratory techniques and potential clinical applications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic kidney disease who are in need of a kidney transplant.
Not a fit: Patients who are not candidates for kidney transplantation or those with acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly increase the availability and success rates of kidney transplants, improving patient outcomes and quality of life.
How similar studies have performed: Previous research has shown promise in organ preservation techniques, but this specific approach using vitrification and nanowarming is relatively novel and untested in clinical settings.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Finger, Erik Brian — University of Minnesota
- Study coordinator: Finger, Erik Brian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.