Improving kidney transplantation outcomes through new therapies
Promoting Kidney Transplantation Tolerance Through Novel Immunomodulation and Cellular Therapy
['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-11063826
This study is exploring new ways to help kidney transplant patients avoid taking lifelong medications that suppress their immune system, using special treatments that help the body accept the new kidney without rejecting it.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-11063826 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing kidney transplantation by promoting immune tolerance, which would allow patients to receive transplants without the need for lifelong immunosuppression. The approach involves using innovative therapies, including specific antibodies that target immune pathways to reduce the body's rejection response to transplanted organs. By collaborating with industry partners, the research aims to evaluate the effectiveness of these novel compounds in inducing tolerance while maintaining protective immunity. This could lead to better long-term health outcomes for kidney transplant recipients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from end-stage kidney disease who are considering or have undergone kidney transplantation.
Not a fit: Patients who are not candidates for kidney transplantation or those with contraindications to immunomodulatory therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the long-term health and quality of life for kidney transplant patients by reducing complications associated with immunosuppression.
How similar studies have performed: Previous research has shown promise in using immunomodulatory therapies to promote transplant tolerance, indicating that this approach has potential for success.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ADAMS, ANDREW B — UNIVERSITY OF MINNESOTA
- Study coordinator: ADAMS, ANDREW B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.