Improving kidney transplant waitlist status for older adults
Official title: Addressing Inactive Kidney Transplant Waitlist Status through Adapting a Tailored Psycho-Social-Environmental Program
Funded at Johns Hopkins University · NIH-11018598 · Data updated 2026-11-12
This study is looking to help older adults waiting for a kidney transplant by providing a special program that offers support and tools to improve their health and well-being while they wait.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | May 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $195,390 |
| NIH project number | 5K23DK133677-03 |
| Project ID | NIH-11018598 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults who are currently on the kidney transplant waitlist but are classified as inactive due to various health and social barriers.
✕Less likely to help
Patients who are not on the kidney transplant waitlist or those who are ineligible for transplantation may not benefit from this research.
What this research studies
This research aims to enhance the outcomes for older adults on the kidney transplant waitlist by implementing a tailored program that addresses various barriers to activation. The program, based on the CAPABLE intervention, focuses on improving symptoms, self-management, social support, and health literacy through a collaborative approach involving healthcare professionals. By equipping patients with the necessary tools and support, the research seeks to reduce waitlist mortality and improve overall quality of life for those awaiting kidney transplants.
Why it matters
Potential benefit: If successful, this research could significantly improve the chances of older adults receiving kidney transplants and enhance their quality of life during the wait.
How similar studies have gone: Previous research using similar community-based interventions has shown success in improving health outcomes for older adults, indicating a promising approach for this population.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Hladek, Melissa — Johns Hopkins University
- Study coordinator: Hladek, Melissa
Related research
Other NIH-funded projects on the same topics.
-
Microbial clues to diagnose and predict infections in kidney transplant patients
A patient-focused project will look for microbial biomarkers in stool, blood, and urine to help doctors predict and diagnose infections in people who have had a kidney transplant.
-
Immunological mechanisms behind treatment-resistant kidney transplant rejection
This grant explores why certain kidney transplant rejections don’t respond to standard treatments and what immune cells in the graft are driving that resistance.
-
Complement-Bound Exosomes and Kidney Transplant Immunity
This project studies how kidney transplant injury and rejection happen after surgery and whether blocking certain immune pathways during organ preservation could improve transplant outcomes.
-
Blood vessel signals predicting heart problems after kidney transplant
This project studies blood markers and tissue patterns after kidney transplants to identify which patients are at highest risk of cardiovascular problems.
-
Understanding how BK virus links infection to kidney transplant rejection
This project looks at how BK polyomavirus reactivation affects kidney transplant patients and aims to use pre-transplant T cell information to tailor immunosuppression and monitoring.
-
Characterization of a LILRB3 SNP cluster and its link to kidney transplant outcomes
A study in kidney transplant recipients looks at genetic factors that may be tied to higher risk of graft failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.