Improving kidney transplant outcomes for children
Advancing Transplantation Outcomes in Children
['FUNDING_U01'] · BOSTON CHILDREN'S HOSPITAL · NIH-10884935
This study is looking for ways to help kids with kidney transplants stay healthy by finding a treatment that keeps their new kidney safe from rejection while still letting their body fight off infections, so they can enjoy better long-term health.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10884935 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the success of kidney transplants in children with end-stage renal disease. It aims to develop an immunosuppressive treatment that minimizes the risk of transplant rejection while preserving the child's ability to fight infections. The study will monitor and identify early signs of inflammation or rejection in the transplanted kidney, using advanced tools and therapies. By addressing these challenges, the research seeks to improve long-term kidney function and overall health in pediatric transplant recipients.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 11 years old who are undergoing or have undergone kidney transplantation.
Not a fit: Patients who are not undergoing kidney transplantation or are over the age of 11 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better kidney transplant outcomes and improved quality of life for children with end-stage renal disease.
How similar studies have performed: Previous research has shown promising results in improving transplant outcomes through innovative immunosuppressive strategies, indicating that this approach has potential for success.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRISCOE, DAVID M. — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: BRISCOE, DAVID M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.