NIH-funded research NIH-funded research

Improving kidney stone outcomes in children

Official title: Personalizing Outcomes of Nephrolithiasis in Youth (PONY) Administrative Core

Funded at Children's Hosp of Philadelphia · NIH-10953810 · Data updated 2026-11-12

This study is all about finding better ways to help kids with kidney stones by working together with top children's hospitals, and it also helps new researchers learn more about treating this condition.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionChildren's Hosp of Philadelphia
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startAugust 1, 2024
Project endMay 31, 2027
Funding year2024
Award (this year)$44,021
NIH project number1P20DK140504-01
Project IDNIH-10953810 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who are experiencing or at risk for nephrolithiasis.

Less likely to help

Patients outside the age range of 0-11 years or those with severe complications from kidney stones may not benefit from this research.

What this research studies

This research focuses on enhancing the understanding and management of kidney stones in children through collaborative efforts among leading children's hospitals. By leveraging existing data and resources, the project aims to identify effective strategies for treating nephrolithiasis in youth. The initiative will also support early-stage researchers in developing their expertise and advancing their careers in pediatric urology. Overall, the goal is to generate impactful knowledge that can lead to better health outcomes for affected children.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options and outcomes for children suffering from kidney stones.

How similar studies have gone: Previous research has shown promise in improving outcomes for pediatric nephrolithiasis, indicating that collaborative approaches can be effective.

Where this research is happening

  • Children's Hosp of Philadelphia
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Tasian, Gregory Edward — Children's Hosp of Philadelphia
  • Study coordinator: Tasian, Gregory Edward

Related research

Other NIH-funded projects on the same topics.

  • Improving kidney stone management in young patients

    This study is all about finding better ways to help kids and young adults under 21 who have kidney stones, by learning more about how these stones develop and how they feel after surgery, so we can create personalized treatment plans just for them.

    NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11159844

  • Improving outcomes for children with kidney stones

    This study is all about helping kids with kidney stones by bringing together top children's hospitals to share ideas and resources, so we can find better ways to treat and manage this condition for healthier futures.

    NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11159841

  • Improving kidney stone treatment for children

    This study is all about finding better ways to help kids with kidney stones feel better and get the right treatment, while also supporting new researchers who want to make a difference in this area.

    NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11159839

  • Understanding how bacteria contribute to kidney stone formation

    This study is looking at how certain bacteria that form biofilms might help create kidney stones, which many people deal with, to find new ways to prevent and treat this common problem.

    NIH research University of California Los Angeles · Los Angeles, United States · NIH-11081818

  • Understanding how citrate and oxalate levels affect kidney stones

    This study is looking at how what we eat affects the levels of citrate and oxalate in the urine, which are important for preventing kidney stones, especially for people who are obese or have had gastric bypass surgery, to help create better ways to keep your kidneys healthy.

    NIH research University of Chicago · Chicago, United States · NIH-11081754

  • Understanding how calcium signaling affects kidney stone formation

    This study is looking at how calcium levels and acidity in the kidneys affect the formation of calcium-based kidney stones, with the hope of finding new ways to help people prevent these stones from forming.

    NIH research U.s. Dept/vets Affairs Medical Center · Washington, United States · NIH-11050052

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.