Improving kidney recovery in patients needing dialysis
CODE-AKI: COnservative Dialysis to Enhance AKI Recovery
This study is looking at whether a more careful approach to dialysis can help people with acute kidney injury recover better than the usual method, and it’s for patients who need dialysis to see if less frequent treatments can lead to improved kidney health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10655505 on NIH RePORTER |
What this research studies
This research investigates a new approach to dialysis for patients suffering from acute kidney injury requiring dialysis (AKI-D). The study aims to determine if a conservative dialysis strategy, where dialysis is only performed when absolutely necessary, can enhance kidney recovery compared to the standard practice of regular dialysis sessions. By conducting a randomized controlled trial with 220 participants, the researchers will also explore the effects of this strategy on kidney injury markers and inflammation. The goal is to provide better outcomes for patients and reduce the duration of dialysis treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are hospitalized patients diagnosed with acute kidney injury requiring dialysis.
Not a fit: Patients with chronic kidney disease or those who are not hospitalized may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved kidney recovery rates and reduced need for prolonged dialysis in hospitalized patients.
How similar studies have performed: Previous pilot studies have shown promise for similar conservative dialysis strategies, indicating potential for success in this larger trial.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Liu, Kathleen D — University of California, San Francisco
- Study coordinator: Liu, Kathleen D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.