Improving kidney preservation for infants and young children
Neonatal and Young Pediatric Kidney Preservation through Nanowarming and Vitrification
This study is looking at new ways to keep kidneys safe for babies and young kids who need a transplant, using special technology to prevent damage during freezing and thawing, so they can find the best match and have a better chance of a successful surgery.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Expanse Bio LLC NIH-funded |
| Lab location | 1 site (North Charleston, United States) |
| Project ID | NIH-11011285 on NIH RePORTER |
What this research studies
This research focuses on enhancing the preservation of kidneys for infants and young children awaiting transplantation. By utilizing advanced nanowarming technology and cryoprotective agents, the team aims to prevent damage during the freezing and thawing processes, which can lead to organ discard. The goal is to extend the viability of kidneys, allowing for better matching between donors and recipients, ultimately increasing the chances of successful transplants for young patients. This innovative approach could also facilitate the use of additional kidneys for older patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and young children who are on the kidney transplant waitlist.
Not a fit: Patients who are not infants or young children, or those who do not require kidney transplantation, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly increase the availability of transplantable kidneys for infants and young children, improving their chances of receiving life-saving transplants.
How similar studies have performed: Other research has shown promise in using similar cryopreservation techniques, but this specific approach with nanowarming technology is relatively novel.
Where this research is happening
North Charleston, United States
- Expanse Bio LLC — North Charleston, United States (Active)
Researchers
- Principal investigator: Weegman, Bradley P — Expanse Bio LLC
- Study coordinator: Weegman, Bradley P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.