Improving kidney preservation for better transplant outcomes
Official title: Platform for Extended Kidney Preservation Via Subnormothermic Perfusion
Funded at Biomedinnovations, INC. · NIH-11013667 · Data updated 2026-11-12
This study is looking at a new way to keep kidneys from older donors and those who have passed away in better shape before they are transplanted, which could help more people waiting for a kidney transplant get a successful match.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biomedinnovations, INC. NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | September 20, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,870,135 |
| NIH project number | 1R44DK139895-01A1 |
| Project ID | NIH-11013667 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients on the kidney transplant waiting list, particularly those who may benefit from high-risk donor kidneys.
✕Less likely to help
Patients who are not on the kidney transplant waiting list or those who are not suitable candidates for transplantation may not receive benefit from this research.
What this research studies
This research focuses on enhancing the preservation of high-risk kidney grafts, particularly those from older donors and donors after circulatory death. By utilizing a novel subnormothermic oxygenated perfusion platform, the study aims to improve the viability and function of these kidneys before transplantation. Patients on the waiting list for kidney transplants may benefit from this approach, as it could increase the number of available donor kidneys and improve transplant success rates. The research involves pilot studies that have shown promising results in animal models, indicating a potential breakthrough in kidney preservation techniques.
Why it matters
Potential benefit: If successful, this research could significantly increase the availability and success rates of kidney transplants for patients in need.
How similar studies have gone: Other research has shown success with similar preservation techniques, indicating a promising avenue for improving kidney transplant outcomes.
Where this research is happening
-
Biomedinnovations, INC.
Denver, United States Active
Researchers
- Principal investigator: Neusner, Robert — Biomedinnovations, INC.
- Study coordinator: Neusner, Robert
Related research
Other NIH-funded projects on the same topics.
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Keeping donated kidneys healthier longer with room-temperature oxygenated perfusion
This project tests a device and special solution that keep donated kidneys at about room temperature with oxygen flowing through them so more high-risk organs might be usable for people needing transplants.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.