Improving kidney health in young children with spina bifida
Urologic Management to Preserve Initial Renal Function Protocol for Young Children with Spina Bifida (UMPIRE)
['FUNDING_U01'] · LURIE CHILDREN'S HOSPITAL OF CHICAGO · NIH-11141540
This study is looking at how to best manage bladder and kidney health in babies with spina bifida, and it aims to find the best treatment methods to help them stay healthy over the next five years.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LURIE CHILDREN'S HOSPITAL OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-11141540 on ClinicalTrials.gov |
What this research studies
This research focuses on the urologic management of infants diagnosed with spina bifida, a condition that affects the spinal cord and can lead to various health complications. The project aims to implement a multi-institutional trial that follows best practices to evaluate how different management strategies impact kidney function and other urologic outcomes. By collecting and analyzing data on renal function, bladder dynamics, and the need for surgical interventions, the researchers hope to refine treatment protocols for better patient outcomes. The study will enroll patients over a five-year period to gather comprehensive clinical data.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and young children diagnosed with spina bifida.
Not a fit: Patients without spina bifida or those who are older than young childhood may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved kidney health and overall urologic management for young children with spina bifida.
How similar studies have performed: Previous research has shown that structured management protocols can significantly improve health outcomes in pediatric populations with similar conditions.
Where this research is happening
CHICAGO, UNITED STATES
- LURIE CHILDREN'S HOSPITAL OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHENG, EARL Y — LURIE CHILDREN'S HOSPITAL OF CHICAGO
- Study coordinator: CHENG, EARL Y
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.