Improving Kidney Function Measurement for Children with Chronic Kidney Disease
The Central Biochemistry Laboratory for the Chronic Kidney Disease in Children Cohort (CKiD)
This project helps measure kidney function in children with chronic kidney disease to better understand their health and development.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11134424 on NIH RePORTER |
What this research studies
This grant supports the ongoing Chronic Kidney Disease in Children (CKiD) study by providing essential laboratory services. Our lab will manage kits and specimens, perform routine diagnostic tests, and conduct specialized kidney biomarker testing. A key focus is accurately measuring kidney filtration rates using a gold-standard method, which helps us understand how kidney disease affects brain development, behavior, social skills, and heart health in young people. We also aim to improve existing equations used to estimate kidney function in children aged 14-17.
Who could benefit from this research
Good fit: This specific grant supports the recruitment of adolescents aged 14-17 with chronic kidney disease for specialized kidney function measurements within the larger CKiD study.
Not a fit: Patients outside the specified age range or those not participating in the CKiD study may not directly benefit from this specific laboratory support.
Why it matters
Potential benefit: If successful, this work will lead to more accurate ways to measure kidney function in children with chronic kidney disease, helping doctors provide better care.
How similar studies have performed: The CKiD study is an established observational cohort, and this grant builds upon its existing framework and previous findings, including the development of a pediatric eGFR equation.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Seegmiller, Jesse C — University of Minnesota
- Study coordinator: Seegmiller, Jesse C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.