Improving kidney cancer surgery with advanced imaging techniques
Advancing Fluorescence Imaging-guided Partial Nephrectomy with ClearICG
This study is looking at a new way to help doctors see kidney tumors better during surgery by using special glowing agents, which could lead to safer operations and better kidney health for patients with kidney cancer.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Clearnano, INC. NIH-funded |
| Lab location | 1 site (Plano, United States) |
| Project ID | NIH-10925420 on NIH RePORTER |
What this research studies
This research focuses on enhancing partial nephrectomy, a surgical procedure for kidney cancer, by using advanced fluorescence imaging to better visualize tumors during surgery. The approach involves the development of new fluorescent agents that can specifically target and highlight cancerous cells, improving the accuracy of tumor removal. By addressing the limitations of current imaging techniques, this research aims to reduce the risk of leaving cancerous tissue behind, which can lead to recurrence and complications. Patients undergoing this procedure may benefit from improved surgical outcomes and preservation of kidney function.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with localized clear cell renal cell carcinoma or papillary renal cell carcinoma who are considering partial nephrectomy.
Not a fit: Patients with advanced kidney cancer or those who are not candidates for partial nephrectomy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective kidney cancer surgeries, reducing the likelihood of cancer recurrence and preserving kidney function.
How similar studies have performed: While there have been advancements in fluorescence imaging for cancer surgery, this specific approach targeting clear cell and papillary renal cell carcinoma is novel and has not been extensively tested.
Where this research is happening
Plano, United States
- Clearnano, INC. — Plano, United States (Active)
Researchers
- Principal investigator: Yu, Mengxiao — Clearnano, INC.
- Study coordinator: Yu, Mengxiao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.