Improving Insulin Delivery for Diabetes Care
A novel inline platform provides an advanced drug delivery device foroptimized diabetes therapy
This project aims to create a new system for delivering insulin under the skin that lasts longer and causes less irritation for people with diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-11125840 on NIH RePORTER |
What this research studies
Current insulin pumps and injections can cause tissue damage and inflammation because of preservatives and insulin clumping, limiting how long they can be worn. This means people often have to change their infusion sites frequently, which is inconvenient and can be painful. This project is developing a new system to reduce these issues by minimizing harmful preservatives and removing clumping insulin. The goal is to create an insulin delivery method that can be worn for much longer, similar to continuous glucose monitors, making diabetes management easier and more comfortable.
Who could benefit from this research
Good fit: Patients with Brittle Diabetes Mellitus or other forms of diabetes who use subcutaneous insulin administration devices might be ideal candidates for future studies related to this technology.
Not a fit: Patients who do not use insulin pumps or subcutaneous injections for their diabetes management would not directly benefit from this specific device improvement.
Why it matters
Potential benefit: If successful, this could lead to insulin delivery devices that last longer, reduce skin irritation, and make daily diabetes management more convenient for patients.
How similar studies have performed: This project proposes a novel inline platform to address issues with insulin preservatives and aggregation, building on preliminary data but representing a new approach to extending wear time.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Klueh, Ulrike — Wayne State University
- Study coordinator: Klueh, Ulrike
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.