Improving informed consent materials for mothers and newborns in HIV research

Strengthening informed consent for authentic participation in perinatal HIV research

['FUNDING_R21'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-11380499

This project uses clear visual consent materials to help breastfeeding mothers, including those living with HIV, understand and decide about joining perinatal research.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorCOLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11380499 on ClinicalTrials.gov

What this research studies

If I am a new mother, the team will offer simple picture-based consent materials to explain what joining a breastfeeding research study means. Columbia and Stellenbosch researchers will test those visual consent forms inside an ongoing trial of a synbiotic given to breastfeeding mother-infant pairs. Social science and empirical ethics experts will interview mothers, observe consent conversations, and collect feedback to find confusing parts and improve the visuals. Those results will shape a larger future trial and help determine whether visuals can replace standard written consent in this setting.

Who could benefit from this research

Good fit: Breastfeeding mothers and their newborns—including mothers living with HIV—recruited shortly after delivery (typically within the first 4 weeks) are the intended participants.

Not a fit: People not enrolled in perinatal or maternal HIV research (such as non-breastfeeding mothers, older children, or individuals outside the study areas) are unlikely to receive direct benefit from this project.

Why it matters

Potential benefit: Could make consent easier to understand so mothers can give truly informed permission and feel more comfortable taking part in perinatal HIV research.

How similar studies have performed: Visual consent approaches have been used in prior maternal-infant studies and show promise, but more data are needed before replacing written forms.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.