Improving immunization rates in children using clinical decision support systems.

Development, validation, and application of a CDS ontology to facilitate CDS rules reuse, management, and maintenance in simulated primary care settings.

NIH-funded research Clemson University · NIH-10885059

This study is working to make it easier for doctors to provide important vaccinations for kids by improving the tools they use in electronic health records, so they can better keep track of what shots children need and help ensure they get them on time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionClemson University NIH-funded
Lab location1 site (Clemson, United States)
Project IDNIH-10885059 on NIH RePORTER

What this research studies

This research focuses on enhancing the effectiveness of clinical decision support (CDS) systems integrated into electronic health records (EHRs) to improve the delivery of preventive care services, particularly immunizations for children. By developing a reusable and machine-interpretable ontology for CDS rules, the project aims to ensure that healthcare providers have access to up-to-date information that can guide their clinical decisions. The methodology involves validating these CDS rules in simulated primary care settings to assess their impact on immunization rates and overall preventive care. This approach seeks to address the gaps in current CDS systems that may lead to missed immunization opportunities.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years, particularly those in primary care settings who are due for immunizations.

Not a fit: Patients who are not within the age range of 0-11 years or those who are not receiving care in primary care settings may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase the rates of recommended immunizations among children, leading to better health outcomes.

How similar studies have performed: Previous research has shown that CDS systems can effectively improve preventive care services, indicating that this approach has potential for success.

Where this research is happening

Clemson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Centers for Disease ControlCenters for Disease Control and PreventionCenters for Disease Control and Prevention (U.S.)Communicable Diseases
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.