Improving immune therapies for heart transplant patients
Targeted immune therapies in heart transplantation
['FUNDING_OTHER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11015852
This study is looking for ways to make heart transplant treatments better by using new methods to help your body accept the new heart while reducing side effects, so if you're a heart transplant patient, you might get to try some exciting new therapies!
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11015852 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing immune therapies used in heart transplantation to prevent organ rejection. It aims to develop innovative strategies that deliver targeted treatments directly to the areas where they are needed most, such as the draining lymph nodes and the transplanted heart. By utilizing advanced techniques like nanotechnology and antibody-drug conjugates, the study seeks to improve the effectiveness of these therapies while minimizing their side effects. Patients participating in this research may receive cutting-edge treatments designed to better manage their post-transplant care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have undergone heart transplantation or are awaiting a heart transplant.
Not a fit: Patients who are not candidates for heart transplantation or those with contraindications to immune therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer immune therapies for heart transplant patients, improving their long-term health and organ survival.
How similar studies have performed: While targeted drug delivery has shown promise in cancer treatment, its application in heart transplantation is still in the early stages, making this research a novel approach.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ABDI, REZA — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: ABDI, REZA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, Cardiac Diseases