Improving immune function to reduce infection risk in spinal cord injury patients
Reducing Infection Susceptibility by Immune Function Restoration in Spinal Cord Injury
This study is looking at new ways to boost the immune system in people with spinal cord injuries to help them avoid infections like pneumonia, using a mix of safe medications that are already approved for use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10871685 on NIH RePORTER |
What this research studies
This research investigates how to enhance the immune system in patients with spinal cord injuries to reduce their risk of infections, particularly pneumonia. It focuses on a novel approach that targets the sympathetic nervous system to restore immune function using a combination of FDA-approved medications. By addressing the immune deficiencies that often follow spinal cord injuries, the study aims to improve patient outcomes and recovery. The research includes experiments to evaluate the effectiveness of these treatments in preventing infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a spinal cord injury and are at risk for infections, particularly pneumonia.
Not a fit: Patients who do not have a spinal cord injury or those with stable immune function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the incidence of infections in spinal cord injury patients, leading to improved health outcomes and recovery rates.
How similar studies have performed: Previous research has shown promise in using neuromodulation techniques to enhance immune function, suggesting that this approach may be effective.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Schwab, Jan — Ohio State University
- Study coordinator: Schwab, Jan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.