Improving imaging technology for detailed cellular analysis

Advancing Multi-Color EM via Direct Detector-enabled 4D-STEM

NIH-funded research University of California, San Diego · NIH-10684732

This study is working on a new imaging technology that helps scientists see and understand the tiny parts of cells better, which could eventually lead to improved tests and treatments for patients like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-10684732 on NIH RePORTER

What this research studies

This research focuses on developing a groundbreaking imaging technology called multicolor electron microscopy (ColorEM) that enhances the ability to visualize and differentiate various molecular complexes within cells and tissues. By utilizing advanced detection devices and innovative software, the project aims to provide high-resolution, three-dimensional imaging that surpasses current methods. This technology will allow for more efficient and accessible imaging, which could lead to better understanding of cellular structures and functions. Patients may benefit indirectly through advancements in diagnostics and treatment strategies that arise from improved cellular imaging.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals with conditions that involve complex cellular structures, such as cancer or genetic disorders.

Not a fit: Patients with conditions that do not involve cellular or molecular complexities may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to significant advancements in the diagnosis and treatment of diseases by providing clearer insights into cellular structures.

How similar studies have performed: Other research has shown success with advanced imaging technologies, indicating a promising potential for this novel approach.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.