Improving imaging techniques to visualize biological processes in tissues
Imaging mass spectrometry at isomeric chemical resolution using gas phase ion/ion reactions
This study is working on a new way to create detailed maps of molecules in tissue samples, which could help us understand how diseases like cancer and diabetes change our bodies, and ultimately lead to better treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10873857 on NIH RePORTER |
What this research studies
This research focuses on enhancing imaging mass spectrometry (IMS) to better visualize and understand biological processes within tissues. By combining the specificity of mass spectrometry with the spatial detail of microscopy, the project aims to create detailed maps of biomolecules in tissue samples. This approach will help identify biochemical pathways that change during diseases like cancer and diabetes, ultimately aiding in the development of new treatment strategies. The research seeks to overcome current limitations in differentiating and identifying complex molecules found in tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with conditions that involve complex biochemical changes, such as cancer or metabolic disorders.
Not a fit: Patients with conditions that do not involve significant biochemical alterations or those who are not undergoing tissue analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and targeted treatments for various diseases, including cancer and diabetes.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to improve our understanding of cellular functions, indicating that this approach could yield significant advancements.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Prentice, Boone M. — University of Florida
- Study coordinator: Prentice, Boone M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.