Improving imaging techniques to study cellular processes in diseases like Alzheimer's.
Two-photon fluorescence lifetime imaging microscopy utilizing the space-time duality
['FUNDING_R21'] · UNIVERSITY OF COLORADO · NIH-11089550
This study is working on a new way to take pictures of cells that helps us see how they work, especially in conditions like Alzheimer's and age-related eye problems, so that doctors can better understand these diseases and improve how they diagnose and treat patients.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO (nih funded) |
| Locations | 1 site (Boulder, UNITED STATES) |
| Trial ID | NIH-11089550 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing fluorescence lifetime imaging microscopy (FLIM), a technology that provides detailed insights into cellular processes by measuring the behavior of fluorescent molecules. By increasing the imaging speed and efficiency, the study aims to better understand cellular metabolism, protein interactions, and the biological environment in conditions such as Alzheimer's disease and age-related macular degeneration. Patients may benefit from improved diagnostic techniques and a deeper understanding of their conditions through this advanced imaging approach.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or age-related macular degeneration.
Not a fit: Patients with conditions unrelated to cellular metabolism or those not affected by Alzheimer's or age-related macular degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and faster diagnostic tools for diseases like Alzheimer's and age-related macular degeneration.
How similar studies have performed: Previous research has shown promise in enhancing imaging techniques for cellular studies, indicating potential success for this novel approach.
Where this research is happening
Boulder, UNITED STATES
- UNIVERSITY OF COLORADO — Boulder, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HUANG, SHU-WEI — UNIVERSITY OF COLORADO
- Study coordinator: HUANG, SHU-WEI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age related macular disease, Alzheimer disease dementia