Improving imaging techniques to observe single molecules in living cells
Toward high spatiotemporal resolution models of single molecules for in vivo applications
['FUNDING_OTHER'] · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · NIH-11045707
This study is working on improving ways to see tiny molecules inside living cells more clearly, which could help doctors track treatments and diagnose diseases better, all while being gentle on the cells being observed.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS (nih funded) |
| Locations | 1 site (TEMPE, UNITED STATES) |
| Trial ID | NIH-11045707 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing imaging methods to observe single molecules within living cells at high resolution. By addressing challenges related to noise and data interpretation, the project aims to develop new mathematical tools that can improve the accuracy of fluorescence imaging. This could lead to better monitoring of therapeutic agents and more effective disease diagnostics. The approach involves innovative techniques that minimize the amount of light needed, reducing potential damage to samples during observation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that require precise monitoring of cellular processes, such as cancer or genetic disorders.
Not a fit: Patients with conditions that do not involve cellular imaging or those who are not undergoing treatment that requires monitoring at the molecular level may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in how diseases are diagnosed and treated by providing clearer insights into cellular processes.
How similar studies have performed: Previous research has shown success in enhancing imaging techniques for single molecules, indicating that this approach has potential for further breakthroughs.
Where this research is happening
TEMPE, UNITED STATES
- ARIZONA STATE UNIVERSITY-TEMPE CAMPUS — TEMPE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PRESSE, STEVE — ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
- Study coordinator: PRESSE, STEVE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.