Improving imaging techniques to assess speech function in children with cleft palate

Using Atlas-driven Imaging for Determining Variations in Velopharyngeal Function Among Children with Cleft Palate and Hypernasal Speech

NIH-funded research University of Illinois at Urbana-Champaign · NIH-10408697

This study is looking at how kids aged 5 to 8 with cleft palate use their mouths and throats when they talk, using special MRI technology to take detailed pictures of their speech movements, which will help doctors understand their needs better and improve treatments for clearer speech.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Urbana-Champaign NIH-funded
Lab location1 site (Champaign, United States)
Project IDNIH-10408697 on NIH RePORTER

What this research studies

This research focuses on developing advanced imaging methods to better understand how children with cleft palate use their vocal tract during speech. By utilizing a dynamic MRI technique, the study aims to capture high-resolution images of speech movements in real-time, specifically targeting children aged 5-8 years old. This innovative approach will provide detailed insights into the velopharyngeal function, which is crucial for diagnosing and planning effective surgical interventions for hypernasal speech. The research seeks to create a comprehensive atlas of normal speech patterns to compare against those of children with cleft palate.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 5-8 years old who have been diagnosed with cleft palate and experience hypernasal speech.

Not a fit: Patients who do not have a cleft palate or are outside the age range of 5-8 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored surgical treatments for children with cleft palate, improving their speech outcomes.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for speech analysis, but this specific dynamic MRI approach is novel and untested in this context.

Where this research is happening

Champaign, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.