Improving imaging techniques for studying cells and tissues
Imaging Cells and Tissues with Super-Resolution Structured Illumination Microscopy
This study is working on a new way to take clearer pictures of tiny parts inside cells, which could help scientists better understand how our bodies work and how diseases develop, ultimately benefiting patients like you.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Colorado Springs, United States) |
| Project ID | NIH-10515036 on NIH RePORTER |
What this research studies
This research focuses on enhancing the resolution of fluorescence microscopy to better visualize biological structures within cells and tissues. By developing super-resolution structured illumination microscopy (SIM), the project aims to overcome current limitations in imaging, which restricts the ability to see smaller cellular components. The approach involves innovating both the optical design and the data processing methods used in SIM, making it more accessible and effective for biologists. Patients may benefit from advancements in understanding cellular functions and disease mechanisms through improved imaging techniques.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions that involve cellular abnormalities or diseases that affect cellular structures.
Not a fit: Patients with conditions unrelated to cellular imaging or those who do not have access to the research facilities may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding cellular processes and disease mechanisms, ultimately improving patient care.
How similar studies have performed: Previous research has shown success with super-resolution microscopy techniques, indicating potential for significant advancements in cellular imaging.
Where this research is happening
Colorado Springs, United States
- University of Colorado — Colorado Springs, United States (Active)
Researchers
- Principal investigator: Hagen, Guy — University of Colorado
- Study coordinator: Hagen, Guy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.