NIH-funded research R01 grant

Improving imaging techniques for human extremities using advanced computer algorithms

Official title: Unsupervised Deep Photon-Counting Computed Tomography Reconstruction for Human Extremity Imaging

Funded at University of Massachusetts Lowell · NIH-11090461 · Data updated 2026-11-12

This study is working on using smart computer technology to make CT scans of arms and legs clearer and safer, so patients can get better pictures of their tissues without as much radiation.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Massachusetts Lowell
NIH-funded
Lab location1 site (Lowell, United States)
Project startJuly 1, 2023
Project endApril 30, 2027
Funding year2025
Award (this year)$561,703
NIH project number5R01EB034737-03
Project IDNIH-11090461 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals requiring imaging of their extremities, such as those with injuries or conditions affecting bones and soft tissues.

Less likely to help

Patients who do not require imaging of their extremities or those with conditions that do not involve the use of CT imaging may not benefit from this research.

What this research studies

This research focuses on enhancing computed tomography (CT) imaging for human extremities by utilizing advanced deep learning algorithms. The approach aims to improve image quality while reducing radiation exposure, making it safer for patients. By leveraging big data, the study seeks to train a deep learning network that can reconstruct high-quality images from x-ray photon-counting CT scans. This could lead to better tissue characterization and more accurate diagnoses.

Why it matters

Potential benefit: If successful, this research could provide patients with safer and more accurate imaging techniques for diagnosing conditions affecting their extremities.

How similar studies have gone: Other research has shown promise in using deep learning for image reconstruction, indicating that this approach could lead to significant advancements in imaging technology.

Where this research is happening

  • University of Massachusetts Lowell
    Lowell, United States
    Active

Researchers

  • Principal investigator: Yu, Hengyong — University of Massachusetts Lowell
  • Study coordinator: Yu, Hengyong

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.