Improving imaging techniques for eye diseases related to oxygen exposure
Official title: Advancing visible-light OCT in oxygen-induced retinopathy
Funded at Oregon Health & Science University · NIH-10941350 · Data updated 2026-11-12
This study is working on a new imaging device to help doctors better see and understand eye problems caused by oxygen in premature babies, which could lead to better ways to diagnose and treat these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $623,090 |
| NIH project number | 1R01EY036429-01 |
| Project ID | NIH-10941350 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include premature infants and individuals at risk for retinopathy of prematurity or other ischemic retinal conditions.
✕Less likely to help
Patients with non-ischemic retinal diseases or those not affected by oxygen-induced retinopathy may not receive any benefit from this research.
What this research studies
This research focuses on enhancing imaging technology to better understand and treat eye diseases caused by oxygen exposure, particularly in premature infants. Using a preclinical model, the study aims to develop a new wide-field imaging device that can capture detailed blood flow and oxygen levels in the retina. By correlating traditional biomarkers with advanced imaging techniques, the research seeks to provide insights into how these conditions develop and respond to treatments. Patients may benefit from improved diagnostic tools and therapies derived from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic and treatment options for patients with retinopathy and other ischemic retinal diseases.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for understanding retinal diseases, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Jia, Yali — Oregon Health & Science University
- Study coordinator: Jia, Yali
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.