Improving imaging techniques for detecting eye changes in neurodegenerative diseases

Achieving specificity in imaging neurodegeneration with visible light Optical Coherence Tomography

NIH-funded research New York University School of Medicine · NIH-11096252

This study is working on a new way to take clearer pictures of the retina to help doctors better understand how diseases like Alzheimer's and Parkinson's affect vision, which could lead to better ways to track and treat these conditions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11096252 on NIH RePORTER

What this research studies

This research focuses on enhancing imaging technology to better visualize changes in the retina associated with neurodegenerative diseases like Alzheimer's and Parkinson's. By developing a new type of optical coherence tomography (OCT) that uses visible light, the researchers aim to achieve higher resolution images of the retina, which can reveal important biomarkers for disease progression. The study will also incorporate machine learning tools to analyze the imaging data, providing a more detailed understanding of how these diseases affect the visual system. This could lead to improved monitoring and treatment strategies for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or Parkinson's disease who are experiencing visual system changes.

Not a fit: Patients with neurodegenerative diseases who do not exhibit any ocular symptoms or changes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection and better management of neurodegenerative diseases through improved retinal imaging.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for understanding neurodegenerative diseases, indicating that this approach could yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's disease patient
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.