Improving imaging techniques for assessing knee osteoarthritis

Development of Sodium Fluoride PET-MRI for Quantitative Assessment of Knee Osteoarthritis

['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-10659207

This study is working on new imaging techniques that combine two types of scans to help us see how knee osteoarthritis changes over time, which could lead to better ways to understand and diagnose your knee health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorSTANFORD UNIVERSITY (nih funded)
Locations1 site (STANFORD, UNITED STATES)
Trial IDNIH-10659207 on ClinicalTrials.gov

What this research studies

This research focuses on developing advanced imaging methods that combine PET and MRI to better understand knee osteoarthritis (OA). By creating a three-dimensional imaging technique, the study aims to quantify changes in bone and soft tissue metabolism in response to joint loading. This innovative approach will allow researchers to track the progression of OA over time and assess how biomechanical changes affect the condition. Patients may benefit from improved diagnostic tools that provide more accurate assessments of their knee health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with knee osteoarthritis who are experiencing joint pain and mobility issues.

Not a fit: Patients with knee osteoarthritis who are not experiencing significant symptoms or those with other unrelated joint conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic methods and treatment strategies for patients suffering from knee osteoarthritis.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for assessing joint conditions, indicating potential success for this novel approach.

Where this research is happening

STANFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: degenerative joint disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.