Improving imaging of retinal blood vessels for eye disease diagnosis

Auto-sensing, instantaneous adaptive ranging OCT

NIH-funded research Massachusetts General Hospital · NIH-11037091

This study is testing a new imaging technology that helps doctors see the tiny blood vessels in your eyes better, which is important for diagnosing eye conditions like diabetic retinopathy and glaucoma, and it involves testing this technology on people to make sure it works well.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11037091 on NIH RePORTER

What this research studies

This research focuses on enhancing the imaging capabilities of retinal blood vessels, which are crucial for diagnosing common eye diseases like diabetic retinopathy and glaucoma. The team aims to develop a new optical coherence tomography angiography (OCTA) technology that can significantly increase the depth range of imaging, allowing for better visualization of peripheral retinal microvasculature. By utilizing advanced photonics technology, they plan to create a fast, tunable optical delay line to improve imaging speed and quality. The effectiveness of this new technology will be validated through tests on human subjects, aiming to establish its clinical utility.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with eye diseases such as diabetic retinopathy, glaucoma, or macular degeneration.

Not a fit: Patients with no retinal vascular issues or those who do not have access to the imaging technology may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and better management of eye diseases, potentially preserving vision for many patients.

How similar studies have performed: Previous research has shown promising results with advanced imaging technologies in ophthalmology, indicating a strong potential for success with this novel approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.